ChatGPT Security for Enterprises: Risks, Best Practices & Solutions

GenAI Security
Blog

Key Takeaways

Control employee data use: ChatGPT security depends on how staff handle inputs and outputs, ensuring no confidential or regulated data is shared in prompts or responses.
Prevent data leakage: Classify and label sensitive data before use, and apply DLP tools to stop exposure of customer details, IP, or internal code.
Set clear access and governance rules: Define who can use ChatGPT, under what conditions, and enforce controls like MFA and identity-based access to reduce “shadow AI” risks.
Maintain real-time visibility: Continuously monitor prompt activity and integrations, automate enforcement to block risky actions, and log usage for compliance reviews.
Discover and assess custom GPTs: Identify which custom GPTs employees are using, evaluate their data handling practices, and understand the risks they pose to enterprise security and compliance.

What is ChatGPT Security?

ChatGPT security refers to the set of controls, governance frameworks, and other initiatives that protect enterprise data, employees, and systems from risks associated with the use of generative AI tools like ChatGPT.

Rather than focusing on the security of the internal mechanics of the model itself, this article centers on the version of ChatGPT security related to how end users engage with the GenAI tool. For instance, what data users share, what information is surfaced, and how those interactions can unintentionally expose business assets.

In the enterprise context, ChatGPT has rapidly become part of daily workflows, from summarizing documents and generating code to creating content and crafting customer communications. While these use cases increase productivity, they also expand the organization’s attack surface.

Employees might inadvertently input confidential project details, customer information, or proprietary code into a prompt. If that data is retained or reused, it can lead to data leakage, compliance violations, or permission sprawl. These are issues that traditional security tools were not designed to handle.

From an enterprise security standpoint, ChatGPT security involves three main dimensions:

  1. Data Exposure Prevention: Understanding what data employees share with ChatGPT and preventing the submission of sensitive, confidential, or regulated information.
  2. Access and Usage Governance: Defining who can use ChatGPT, under what conditions, and with which datasets. This includes aligning access controls with enterprise identity systems and monitoring for unauthorized or “shadow” AI usage.
  3. Visibility and Continuous Monitoring: Gaining real-time insight into how ChatGPT is being used across the organization—including activity within employee-built custom GPTs—so teams can track prompt behavior, detect oversharing, and enforce policies that keep sensitive data within approved boundaries.

Why ChatGPT Security is Critical for Enterprises

Enterprises are rapidly integrating ChatGPT into everyday workflows to boost productivity, automate communication, and support decision-making. But as usage grows, so do the risks of unmonitored prompts, oversharing of data, and potential compliance violations. ChatGPT security ensures that employees use this tool securely and in compliance with regulatory requirements and corporate governance policies.

  • Protects Sensitive Enterprise Data: Employees may unknowingly share internal documents, client information, or intellectual property in ChatGPT prompts. ChatGPT security frameworks help prevent data leakage and ensure sensitive information remains confidential across interactions.
  • Prevents Business Disruption: When AI tools are used without clear usage policies, they can create misinformation, system conflicts, or workflow delays. Proactive oversight and clear controls help keep operations stable and ensure that AI-driven processes function smoothly.
  • Meets Compliance and Regulatory Demands: Industries like finance, healthcare, and technology operate under strict regulatory mandates like GDPR, HIPAA, and PCI DSS. Non-compliance can lead to violations or penalties. Establishing ChatGPT security controls ensures adherence to those regulations.

Key ChatGPT Security Risks

Enterprises face several distinct security challenges when scaling ChatGPT use across teams. These risks often stem from unmonitored interactions, integrations, and data handling practices. By understanding these risks, organizations can design safeguards that enable them to maintain control and compliance.

Risk Description
Data Leakage and Retention Risks Employees may share internal data, customer details, or trade secrets in prompts. If not managed, this information can be retained or resurfaced, creating exposure and regulatory risk.
Prompt Injection and Malicious Prompts Prompt injection and malicious prompts can alter the AI’s behavior, extract unintended information, or produce harmful responses that mislead users or reveal sensitive data.
Unauthorized Access and Account Compromise Weak authentication or shared logins increase the chance of unauthorized access to enterprise ChatGPT environments, leading to data misuse or unauthorized queries.
Plugin and Integration Vulnerabilities Third-party ChatGPT plugins or connectors can create data flow vulnerabilities if permissions are misconfigured or APIs are not properly secured.
Custom GPTs and Unapproved Usage Employees may discover, use, or create their own custom GPTs - either publicly available or built by third parties - without IT oversight. These custom GPTs can have unknown data handling practices, undisclosed integrations, and varying security controls, leading to potential data exposure, IP leakage, and compliance violations outside the enterprise's governed environment.
Output Reliability and Sensitive Inference Model outputs that infer or reconstruct sensitive facts from context, leading to inadvertent disclosure or poor decisions.


Real-World Examples of ChatGPT Security Risks

Even well-intentioned employees can expose sensitive data when using ChatGPT in the absence of proper controls. The following real-world examples highlight how common workplace behaviors can translate into security risks and why visibility and governance are critical to prevent them:

Employee Oversharing of Sensitive Data in ChatGPT

In 2023, Samsung engineers reportedly pasted confidential source code and internal notes into ChatGPT, unintentionally exposing proprietary data. The incident led the company to ban generative AI tools for employees, highlighting how quickly convenience-driven LLM use can escalate into a severe data governance issue.

Unauthorized Use of ChatGPT Plugins or Third-Party Integrations

A security researcher reported discovering critical vulnerabilities within ChatGPT’s plugin ecosystem, where improper permission handling could expose user data and API keys. While these issues were responsibly disclosed, they highlight how quickly integrations can expand the attack surface.

Misconfigured Access and Shadow ChatGPT Instances in Enterprises

20% of organizations reported breaches linked to shadow AI, where unapproved AI tools operated outside security oversight. These incidents added an average of US$ 670,000 to breach costs, underscoring the financial and operational impact of unmanaged AI use within enterprises.

How ChatGPT Handles Data and Privacy

Enterprises that handle regulated or sensitive information need to understand how ChatGPT processes and retains data. While the platform offers convenience and automation, it also introduces privacy considerations that security and compliance teams must evaluate before large-scale deployment.

When users interact with ChatGPT, their prompts and responses typically travel through cloud infrastructure. Depending on the service plan and configuration, this data may be logged temporarily for system performance monitoring, abuse detection, or other operational purposes.

For the ChatGPT Enterprise plan, OpenAI states that customer prompts and company data are not used to train models by default. These enterprise-class offerings also provide enhanced administrative tools, encryption, and support for compliance standards (such as SOC 2 and GDPR).

However, even in approved enterprise environments, ChatGPT's web search capability introduces additional risk. When users enable web browsing, the AI can retrieve and reference external content to answer queries. This creates potential exposure if users inadvertently share sensitive context in prompts that trigger web searches, or if ChatGPT surfaces information from untrusted or malicious sources. Organizations need visibility into when and how web search is being used, and should consider restricting this feature for roles handling confidential data.

By contrast, prompts from free or individual-user accounts may be used for model improvement unless the user actively opts out. This distinction underscores why enterprises should deploy only approved, centrally managed ChatGPT environments integrated with corporate identity and access management (IAM) systems, data classification, retention policies, and full visibility of usage.

Enterprise Controls and Data Governance for ChatGPT Security

To ensure ChatGPT is used safely across the enterprise, organizations need more than just written policies. They must apply strong controls that automatically enforce data protection and governance at every stage of AI interaction. By embedding visibility, monitoring, and policy automation into ChatGPT use, enterprises can reduce the risk of data exposure. The following controls outline practical steps enterprises can take to manage ChatGPT usage securely:

  1. Establish AI Data Usage Policies: Define what employees can and cannot share with ChatGPT. Policies should be centralized and clearly specify approved AI tools, data categories that are off-limits, and workflows for submitting sensitive content. Centralized policies reduce guesswork and create consistency across departments.
  2. Classify Sensitive Data Before Using in Prompts: Data classification helps in efforts to automatically identify confidential or regulated information before employees include it in ChatGPT interactions. These efforts can be enhanced by integrating data-loss prevention (DLP) tools and sensitivity labels.
  3. Monitor and Audit Prompt Activity: Continuous monitoring of ChatGPT usage helps security teams identify oversharing, suspicious prompts, or unapproved integrations. Audit logs provide traceability for compliance reviews and incident response operations.
  4. Ensure Policy Enforcement Through Automation: Automated enforcement tools can block risky prompts, alert security teams, or restrict access based on user roles without requiring human intervention. This ensures governance policies are applied consistently in real-time rather than relying on manual oversight.
  5. Detect Unauthorized AI Use and Shadow ChatGPT Instances: Monitor networks for unapproved ChatGPT access or external AI tools. Discovering and mitigating “shadow AI” helps keep all usage visible, controlled, and aligned with enterprise governance policies.
  6. Deploy Custom GPTs with Controlled Data Access: For enterprise deployments, leverage Custom GPTs that can be configured with specific instructions, knowledge bases, and access controls. Custom GPTs allow organizations to pre-define acceptable use cases, limit web search capabilities, and restrict data sources while still delivering AI productivity gains. This approach creates guardrails that prevent users from accidentally exposing sensitive data through open-ended prompts or uncontrolled web browsing features.
  7. Track Prompt-Level Activity and Oversharing: Prompt-level insights reveal how employees interact with ChatGPT and where sensitive data may appear. These findings, in turn, help organizations improve governance policies.
  8. Report AI Usage Insights to Security Teams: These reports provide leadership with a clear picture of AI adoption, data movement, and policy effectiveness. These insights likewise enable security leaders to connect AI governance efforts with broader enterprise risk and compliance objectives.

Governance and Compliance Frameworks for ChatGPT Use

ChatGPT use in enterprises must operate within clear governance and compliance boundaries. As regulatory bodies introduce AI-specific requirements, organizations need to align ChatGPT usage policies with global data protection laws, industry standards, and internal governance frameworks.

Mapping ChatGPT Use to Global Regulations

Enterprises should evaluate how ChatGPT usage interacts with privacy and data protection requirements such as GDPR, HIPAA, and the California Consumer Privacy Act (CCPA). These regulations emphasize accountability, user consent, and data minimization, which are principles that also apply to AI interactions. 

In the EU, the AI Act further requires risk classification and governance documentation for high-risk AI applications, while global standards such as ISO/IEC 42001 provide structured frameworks for managing AI responsibly. 

As part of regulatory compliance initiatives, organizations must document how ChatGPT is used across the enterprise, maintain audit trails for AI interactions, and verify that data processing aligns with applicable privacy and retention requirements.

Aligning Policies with Enterprise Governance Standards

Enterprises can strengthen ChatGPT oversight by embedding it into their existing governance frameworks instead of creating new, isolated policies. Integrating ChatGPT management into enterprise controls ensures consistent enforcement of security, privacy, and compliance standards across teams.

Established frameworks such as NIST’s AI Risk Management Framework (AI RMF), ISO/IEC 27001, and internal Information Security Management Systems (ISMS) provide ready-made references for assessing AI risks, defining acceptable use, and monitoring compliance. These frameworks also help enterprises formalize processes like access control, incident response, and data classification for ChatGPT environments.

Furthermore, when ChatGPT oversight is embedded within these enterprise frameworks, it encourages collaboration among IT, security, and compliance teams. This alignment not only streamlines governance but also supports scalable, secure AI adoption.

Best Practices for Secure ChatGPT Use

Enterprises adopting ChatGPT need practical, enforceable measures that reduce risk without restricting productivity. The goal is to balance innovation with control, allowing employees to benefit from AI while keeping sensitive data and intellectual property protected. These best practices serve as a practical guide for enterprises to maintain secure and compliant ChatGPT use:

Best Practice Description
Secure and Monitor Custom GPT Configurations Create Custom GPTs with pre-configured guardrails that restrict data access, web search, and prompt patterns. Continuously monitor their intent, data connections, integrated tooling, and usage patterns to identify risks. Track how employees interact with Custom GPTs to detect misuse, oversharing, or unauthorized configuration changes.
Limit Sensitive Information in Prompts Employees should avoid entering any data classified as confidential, regulated, or proprietary into ChatGPT. This includes customer information, credentials, or internal code. Regular awareness training helps reinforce knowledge on what data should never be shared.
Apply Multi-Factor Authentication (MFA) Require Multi-Factor Authentication (MFA) for all enterprise-managed ChatGPT accounts (i.e., those integrated via corporate identity or APIs). MFA introduces a second factor of verification, which significantly reduces the risk of unauthorized logins, and is especially essential when accounts are federated via identity providers or exposed to API access.
Enable Logging and Regular Audits Maintain detailed logs of ChatGPT interactions and monitor for inappropriate data sharing or policy violations. Periodic audits of prompt activity, user access, and API integrations help detect anomalies early and ensure accountability.
Use Private or Managed ChatGPT Environments Where possible, deploy ChatGPT through enterprise plans that offer data privacy controls and centralized administration. Private instances ensure that data is processed securely and not used for model training, aligning with regulatory and governance requirements.
Train Employees on AI Security Policies Human behavior is one of the largest variables in AI risk. To minimize risk involving the human element, conduct regular training sessions that cover acceptable use, data classification, and escalation paths for incidents involving AI tools.
Constrain System Prompts and Integrations Review pre-filled context, retrieval sources, and API keys to ensure system prompts and connectors don’t inadvertently expose sensitive data.


How Opsin Strengthens ChatGPT Security for Enterprises

Enterprises deploying AI tools like ChatGPT often face increased exposure when data access and user activity are not properly governed. Opsin addresses these challenges through a layered approach that combines risk assessment, visibility, policy enforcement, and automated response. The following capabilities demonstrate how Opsin strengthens ChatGPT security and helps enterprises manage AI use:

  • AI Risk Assessment and Continuous Visibility: Opsin begins with a proactive risk-assessment to uncover hidden risks tied to ChatGPT Enterprise, including oversharing, risky user behavior, and sensitive data exposure within integrated systems. By providing prioritized risk insights and enabling continuous monitoring of usage, the approach gives security teams a clear and actionable starting point for identifying what sensitive information is at risk.
  • Discovery and Monitoring of Custom GPTs: Opsin continuously discovers Custom GPTs across the organization and monitors their configurations, data connections, and usage patterns. It detects prompt behaviors and data flows outside official governance, identifying Custom GPTs that pose risk due to their intent, tooling, or how employees are using them.
  • Real-Time Detection and Response to AI Policy Violations: Opsin provides real-time monitoring of AI interactions to detect violations of AI usage policies, sensitive data exposure through prompts, and risky user behavior patterns. When violations occur, the system captures full context around the incident - enabling security teams to investigate thoroughly and respond immediately. Opsin also surfaces the most risky users across the organization, allowing teams to identify high-risk behavior patterns and mitigate exposure before incidents escalate.

Conclusion

As enterprises integrate ChatGPT into daily operations, security and governance must evolve to keep pace with adoption. Effective ChatGPT security focuses on protecting data, maintaining compliance, and ensuring that AI use remains transparent and accountable. By combining data protection, continuous visibility, and automated policy enforcement, organizations can minimize exposure while enabling safe and efficient AI adoption.

Platforms like Opsin strengthen this foundation by giving enterprises the visibility and control needed to manage generative AI securely. With the right frameworks, oversight, and technology in place, businesses can harness ChatGPT’s potential responsibly and turn innovation into a secure, sustainable advantage.

Table of Contents

FAQ

What’s the difference between ChatGPT data privacy and ChatGPT security?

ChatGPT privacy protects user data from misuse, while security enforces how that data is stored, shared, and governed within enterprise systems.

• Establish explicit data classification rules for prompts.
• Enable encryption and anonymization of all AI interactions.
• Integrate privacy assessments into AI deployment reviews.

See how enterprises balance these concerns in “Generative AI and Zero Trust: Navigating the Future of GenAI Security”.

How can employees safely use ChatGPT without exposing company data?

Employees should avoid submitting regulated or internal data, and use only approved enterprise ChatGPT environments.

  • Train users on AI data-handling policies and acceptable prompts.
  • Use managed enterprise ChatGPT or Opsin-integrated instances.
  • Monitor for policy violations.

How do prompt injection attacks compromise ChatGPT security?

Prompt injection manipulates AI instructions to exfiltrate or corrupt data.

  • Sanitize and validate user input to neutralize hidden commands.
  • Monitor for abnormal prompt patterns or large outbound responses.
  • Restrict system prompt modifications through access control.

What frameworks help enterprises govern ChatGPT securely at scale?

NIST AI RMF and ISO/IEC 42001 provide structured ways to assess, monitor, and document AI risk.

  • Map ChatGPT use to GDPR, HIPAA, and CCPA compliance.
  • Embed AI policies into existing ISMS or SOX frameworks.
  • Automate audit logging and retention across AI workflows.

Opsin’s AI Readiness Assessment helps enterprises align ChatGPT governance with these global standards.

How does Opsin’s AI Detection and Response differ from traditional DLP?

Traditional DLP tools focus on preventing static data loss, while Opsin continuously monitors live AI interactions and responds in real time.

  • Real-Time Policy Enforcement: Detects AI policy violations, sensitive data exposure in prompts, and risky user behavior as they happen.
  • Full Incident Context: Captures prompt content, accessed data sources, user activity history, and risk indicators for complete investigation visibility.
  • Automated Response: Enables instant alerts and remediation workflows to contain violations before they escalate.
  • User Risk Insights: Dashboards highlight the most at-risk users and behavioral trends across the organization for proactive mitigation.

Opsin delivers dynamic, AI-aware protection that traditional DLP solutions weren’t built to provide. Explore Opsin’s AI Detection and Response solution.

About the Author
LinkedIn Bio >

ChatGPT Security for Enterprises: Risks, Best Practices & Solutions

What is ChatGPT Security?

ChatGPT security refers to the set of controls, governance frameworks, and other initiatives that protect enterprise data, employees, and systems from risks associated with the use of generative AI tools like ChatGPT.

Rather than focusing on the security of the internal mechanics of the model itself, this article centers on the version of ChatGPT security related to how end users engage with the GenAI tool. For instance, what data users share, what information is surfaced, and how those interactions can unintentionally expose business assets.

In the enterprise context, ChatGPT has rapidly become part of daily workflows, from summarizing documents and generating code to creating content and crafting customer communications. While these use cases increase productivity, they also expand the organization’s attack surface.

Employees might inadvertently input confidential project details, customer information, or proprietary code into a prompt. If that data is retained or reused, it can lead to data leakage, compliance violations, or permission sprawl. These are issues that traditional security tools were not designed to handle.

From an enterprise security standpoint, ChatGPT security involves three main dimensions:

  1. Data Exposure Prevention: Understanding what data employees share with ChatGPT and preventing the submission of sensitive, confidential, or regulated information.
  2. Access and Usage Governance: Defining who can use ChatGPT, under what conditions, and with which datasets. This includes aligning access controls with enterprise identity systems and monitoring for unauthorized or “shadow” AI usage.
  3. Visibility and Continuous Monitoring: Gaining real-time insight into how ChatGPT is being used across the organization—including activity within employee-built custom GPTs—so teams can track prompt behavior, detect oversharing, and enforce policies that keep sensitive data within approved boundaries.

Why ChatGPT Security is Critical for Enterprises

Enterprises are rapidly integrating ChatGPT into everyday workflows to boost productivity, automate communication, and support decision-making. But as usage grows, so do the risks of unmonitored prompts, oversharing of data, and potential compliance violations. ChatGPT security ensures that employees use this tool securely and in compliance with regulatory requirements and corporate governance policies.

  • Protects Sensitive Enterprise Data: Employees may unknowingly share internal documents, client information, or intellectual property in ChatGPT prompts. ChatGPT security frameworks help prevent data leakage and ensure sensitive information remains confidential across interactions.
  • Prevents Business Disruption: When AI tools are used without clear usage policies, they can create misinformation, system conflicts, or workflow delays. Proactive oversight and clear controls help keep operations stable and ensure that AI-driven processes function smoothly.
  • Meets Compliance and Regulatory Demands: Industries like finance, healthcare, and technology operate under strict regulatory mandates like GDPR, HIPAA, and PCI DSS. Non-compliance can lead to violations or penalties. Establishing ChatGPT security controls ensures adherence to those regulations.

Key ChatGPT Security Risks

Enterprises face several distinct security challenges when scaling ChatGPT use across teams. These risks often stem from unmonitored interactions, integrations, and data handling practices. By understanding these risks, organizations can design safeguards that enable them to maintain control and compliance.

Risk Description
Data Leakage and Retention Risks Employees may share internal data, customer details, or trade secrets in prompts. If not managed, this information can be retained or resurfaced, creating exposure and regulatory risk.
Prompt Injection and Malicious Prompts Prompt injection and malicious prompts can alter the AI’s behavior, extract unintended information, or produce harmful responses that mislead users or reveal sensitive data.
Unauthorized Access and Account Compromise Weak authentication or shared logins increase the chance of unauthorized access to enterprise ChatGPT environments, leading to data misuse or unauthorized queries.
Plugin and Integration Vulnerabilities Third-party ChatGPT plugins or connectors can create data flow vulnerabilities if permissions are misconfigured or APIs are not properly secured.
Custom GPTs and Unapproved Usage Employees may discover, use, or create their own custom GPTs - either publicly available or built by third parties - without IT oversight. These custom GPTs can have unknown data handling practices, undisclosed integrations, and varying security controls, leading to potential data exposure, IP leakage, and compliance violations outside the enterprise's governed environment.
Output Reliability and Sensitive Inference Model outputs that infer or reconstruct sensitive facts from context, leading to inadvertent disclosure or poor decisions.


Real-World Examples of ChatGPT Security Risks

Even well-intentioned employees can expose sensitive data when using ChatGPT in the absence of proper controls. The following real-world examples highlight how common workplace behaviors can translate into security risks and why visibility and governance are critical to prevent them:

Employee Oversharing of Sensitive Data in ChatGPT

In 2023, Samsung engineers reportedly pasted confidential source code and internal notes into ChatGPT, unintentionally exposing proprietary data. The incident led the company to ban generative AI tools for employees, highlighting how quickly convenience-driven LLM use can escalate into a severe data governance issue.

Unauthorized Use of ChatGPT Plugins or Third-Party Integrations

A security researcher reported discovering critical vulnerabilities within ChatGPT’s plugin ecosystem, where improper permission handling could expose user data and API keys. While these issues were responsibly disclosed, they highlight how quickly integrations can expand the attack surface.

Misconfigured Access and Shadow ChatGPT Instances in Enterprises

20% of organizations reported breaches linked to shadow AI, where unapproved AI tools operated outside security oversight. These incidents added an average of US$ 670,000 to breach costs, underscoring the financial and operational impact of unmanaged AI use within enterprises.

How ChatGPT Handles Data and Privacy

Enterprises that handle regulated or sensitive information need to understand how ChatGPT processes and retains data. While the platform offers convenience and automation, it also introduces privacy considerations that security and compliance teams must evaluate before large-scale deployment.

When users interact with ChatGPT, their prompts and responses typically travel through cloud infrastructure. Depending on the service plan and configuration, this data may be logged temporarily for system performance monitoring, abuse detection, or other operational purposes.

For the ChatGPT Enterprise plan, OpenAI states that customer prompts and company data are not used to train models by default. These enterprise-class offerings also provide enhanced administrative tools, encryption, and support for compliance standards (such as SOC 2 and GDPR).

However, even in approved enterprise environments, ChatGPT's web search capability introduces additional risk. When users enable web browsing, the AI can retrieve and reference external content to answer queries. This creates potential exposure if users inadvertently share sensitive context in prompts that trigger web searches, or if ChatGPT surfaces information from untrusted or malicious sources. Organizations need visibility into when and how web search is being used, and should consider restricting this feature for roles handling confidential data.

By contrast, prompts from free or individual-user accounts may be used for model improvement unless the user actively opts out. This distinction underscores why enterprises should deploy only approved, centrally managed ChatGPT environments integrated with corporate identity and access management (IAM) systems, data classification, retention policies, and full visibility of usage.

Enterprise Controls and Data Governance for ChatGPT Security

To ensure ChatGPT is used safely across the enterprise, organizations need more than just written policies. They must apply strong controls that automatically enforce data protection and governance at every stage of AI interaction. By embedding visibility, monitoring, and policy automation into ChatGPT use, enterprises can reduce the risk of data exposure. The following controls outline practical steps enterprises can take to manage ChatGPT usage securely:

  1. Establish AI Data Usage Policies: Define what employees can and cannot share with ChatGPT. Policies should be centralized and clearly specify approved AI tools, data categories that are off-limits, and workflows for submitting sensitive content. Centralized policies reduce guesswork and create consistency across departments.
  2. Classify Sensitive Data Before Using in Prompts: Data classification helps in efforts to automatically identify confidential or regulated information before employees include it in ChatGPT interactions. These efforts can be enhanced by integrating data-loss prevention (DLP) tools and sensitivity labels.
  3. Monitor and Audit Prompt Activity: Continuous monitoring of ChatGPT usage helps security teams identify oversharing, suspicious prompts, or unapproved integrations. Audit logs provide traceability for compliance reviews and incident response operations.
  4. Ensure Policy Enforcement Through Automation: Automated enforcement tools can block risky prompts, alert security teams, or restrict access based on user roles without requiring human intervention. This ensures governance policies are applied consistently in real-time rather than relying on manual oversight.
  5. Detect Unauthorized AI Use and Shadow ChatGPT Instances: Monitor networks for unapproved ChatGPT access or external AI tools. Discovering and mitigating “shadow AI” helps keep all usage visible, controlled, and aligned with enterprise governance policies.
  6. Deploy Custom GPTs with Controlled Data Access: For enterprise deployments, leverage Custom GPTs that can be configured with specific instructions, knowledge bases, and access controls. Custom GPTs allow organizations to pre-define acceptable use cases, limit web search capabilities, and restrict data sources while still delivering AI productivity gains. This approach creates guardrails that prevent users from accidentally exposing sensitive data through open-ended prompts or uncontrolled web browsing features.
  7. Track Prompt-Level Activity and Oversharing: Prompt-level insights reveal how employees interact with ChatGPT and where sensitive data may appear. These findings, in turn, help organizations improve governance policies.
  8. Report AI Usage Insights to Security Teams: These reports provide leadership with a clear picture of AI adoption, data movement, and policy effectiveness. These insights likewise enable security leaders to connect AI governance efforts with broader enterprise risk and compliance objectives.

Governance and Compliance Frameworks for ChatGPT Use

ChatGPT use in enterprises must operate within clear governance and compliance boundaries. As regulatory bodies introduce AI-specific requirements, organizations need to align ChatGPT usage policies with global data protection laws, industry standards, and internal governance frameworks.

Mapping ChatGPT Use to Global Regulations

Enterprises should evaluate how ChatGPT usage interacts with privacy and data protection requirements such as GDPR, HIPAA, and the California Consumer Privacy Act (CCPA). These regulations emphasize accountability, user consent, and data minimization, which are principles that also apply to AI interactions. 

In the EU, the AI Act further requires risk classification and governance documentation for high-risk AI applications, while global standards such as ISO/IEC 42001 provide structured frameworks for managing AI responsibly. 

As part of regulatory compliance initiatives, organizations must document how ChatGPT is used across the enterprise, maintain audit trails for AI interactions, and verify that data processing aligns with applicable privacy and retention requirements.

Aligning Policies with Enterprise Governance Standards

Enterprises can strengthen ChatGPT oversight by embedding it into their existing governance frameworks instead of creating new, isolated policies. Integrating ChatGPT management into enterprise controls ensures consistent enforcement of security, privacy, and compliance standards across teams.

Established frameworks such as NIST’s AI Risk Management Framework (AI RMF), ISO/IEC 27001, and internal Information Security Management Systems (ISMS) provide ready-made references for assessing AI risks, defining acceptable use, and monitoring compliance. These frameworks also help enterprises formalize processes like access control, incident response, and data classification for ChatGPT environments.

Furthermore, when ChatGPT oversight is embedded within these enterprise frameworks, it encourages collaboration among IT, security, and compliance teams. This alignment not only streamlines governance but also supports scalable, secure AI adoption.

Best Practices for Secure ChatGPT Use

Enterprises adopting ChatGPT need practical, enforceable measures that reduce risk without restricting productivity. The goal is to balance innovation with control, allowing employees to benefit from AI while keeping sensitive data and intellectual property protected. These best practices serve as a practical guide for enterprises to maintain secure and compliant ChatGPT use:

Best Practice Description
Secure and Monitor Custom GPT Configurations Create Custom GPTs with pre-configured guardrails that restrict data access, web search, and prompt patterns. Continuously monitor their intent, data connections, integrated tooling, and usage patterns to identify risks. Track how employees interact with Custom GPTs to detect misuse, oversharing, or unauthorized configuration changes.
Limit Sensitive Information in Prompts Employees should avoid entering any data classified as confidential, regulated, or proprietary into ChatGPT. This includes customer information, credentials, or internal code. Regular awareness training helps reinforce knowledge on what data should never be shared.
Apply Multi-Factor Authentication (MFA) Require Multi-Factor Authentication (MFA) for all enterprise-managed ChatGPT accounts (i.e., those integrated via corporate identity or APIs). MFA introduces a second factor of verification, which significantly reduces the risk of unauthorized logins, and is especially essential when accounts are federated via identity providers or exposed to API access.
Enable Logging and Regular Audits Maintain detailed logs of ChatGPT interactions and monitor for inappropriate data sharing or policy violations. Periodic audits of prompt activity, user access, and API integrations help detect anomalies early and ensure accountability.
Use Private or Managed ChatGPT Environments Where possible, deploy ChatGPT through enterprise plans that offer data privacy controls and centralized administration. Private instances ensure that data is processed securely and not used for model training, aligning with regulatory and governance requirements.
Train Employees on AI Security Policies Human behavior is one of the largest variables in AI risk. To minimize risk involving the human element, conduct regular training sessions that cover acceptable use, data classification, and escalation paths for incidents involving AI tools.
Constrain System Prompts and Integrations Review pre-filled context, retrieval sources, and API keys to ensure system prompts and connectors don’t inadvertently expose sensitive data.


How Opsin Strengthens ChatGPT Security for Enterprises

Enterprises deploying AI tools like ChatGPT often face increased exposure when data access and user activity are not properly governed. Opsin addresses these challenges through a layered approach that combines risk assessment, visibility, policy enforcement, and automated response. The following capabilities demonstrate how Opsin strengthens ChatGPT security and helps enterprises manage AI use:

  • AI Risk Assessment and Continuous Visibility: Opsin begins with a proactive risk-assessment to uncover hidden risks tied to ChatGPT Enterprise, including oversharing, risky user behavior, and sensitive data exposure within integrated systems. By providing prioritized risk insights and enabling continuous monitoring of usage, the approach gives security teams a clear and actionable starting point for identifying what sensitive information is at risk.
  • Discovery and Monitoring of Custom GPTs: Opsin continuously discovers Custom GPTs across the organization and monitors their configurations, data connections, and usage patterns. It detects prompt behaviors and data flows outside official governance, identifying Custom GPTs that pose risk due to their intent, tooling, or how employees are using them.
  • Real-Time Detection and Response to AI Policy Violations: Opsin provides real-time monitoring of AI interactions to detect violations of AI usage policies, sensitive data exposure through prompts, and risky user behavior patterns. When violations occur, the system captures full context around the incident - enabling security teams to investigate thoroughly and respond immediately. Opsin also surfaces the most risky users across the organization, allowing teams to identify high-risk behavior patterns and mitigate exposure before incidents escalate.

Conclusion

As enterprises integrate ChatGPT into daily operations, security and governance must evolve to keep pace with adoption. Effective ChatGPT security focuses on protecting data, maintaining compliance, and ensuring that AI use remains transparent and accountable. By combining data protection, continuous visibility, and automated policy enforcement, organizations can minimize exposure while enabling safe and efficient AI adoption.

Platforms like Opsin strengthen this foundation by giving enterprises the visibility and control needed to manage generative AI securely. With the right frameworks, oversight, and technology in place, businesses can harness ChatGPT’s potential responsibly and turn innovation into a secure, sustainable advantage.

Get Your Copy
Your Name*
Job Title*
Business Email*
Your copy
is ready!
Please check for errors and try again.

Secure, govern, and scale AI

Inventory AI, secure data, and stop insider threats
Book a Demo →